2014 ICAD program


Schedule at a Glace

Friday 31, Oct, 2014   

12:00-21:00 pm Registration


Saturday 1, Nov, 2014 (Conference Room No.305)

8:30am -9:00am    Opening Ceremony

9:00am -9:15am    Group Photo

9:15am -10:15am    Key Note Speech

10:15am -10:30am    Coffee Break

10:30am -11:30am    Key Note Speech

12:00pm- 1:00pm     Lunch (2rd floor, Lijiang Hall)

1:00pm- 3:05pm       Session 1: Stem Cells, Aging and Disease

3:05pm- 3:25pm       Coffee Break

3:25pm- 5:30pm       Session 2: System aging and Disease

6:30pm-8:30pm        Welcome Dinner (2rd floor, Lijiang Hall)


Sunday 2, Nov, 2014 (Conference Room No.305)

8:30am-10:30am      Session3: Age-Related Neurodegenerative Diseases

10:30am-10:45am     Coffee Break

10:45am- 12:00am    Session 4: Aging and Cardiovascular Diseases

12:00pm- 1:00pm     Lunch (2rd floor, Lijiang Hall)

1:00pm- 3:00pm      Session 5: Aging and Stroke

3:00pm- 3:15pm      Coffee Break

3:15am-5:00pm       Session 6: Aging, Metabolism, hormone and Diseases

5:00pm-5:20pm      Close Mark


Sunday 2, Nov, 2014 (Conference Room No.201)

8:30am-10:35am    Session 7: Genetics, Aging and Disease

10:35am-10:45am    Coffee Break

10:45pm-12:00pm   Session 8: Aging, DNA Damage, Telomeres, Protein oxidation and Disease

12:00pm- 1:00pm     Lunch (2rd floor, Lijiang Hall)

1:00pm-3:05pm    Session 9: Aging, immune and translation

3:05pm-3:20pm  Coffee Break

3:20pm -5:00pm  Session 10: HIV/AIDS and aging

5:00pm-5:20pm    Close Mark (room 305)


Monday 3, Nov, 2014 


Great wall trip (speaker only)

7:30 am: gathering in the hotel lobby


Conference program is available at conference room 305 (8:00am, Nov. 1, 2014)

Conference Program


Friday, 31 Oct, 2014




Saturday 1 Nov, 2014Conference Room No.305

8:30 AM  -  9:00 AM







9:00AM  -  9:15 AM

Opening Ceremony

Chair: Kunlin Jin and Xunming Ji

Xunming Ji

James W. Simpkins

Heqi Cao

Liping Zhang


Group photo            

9:15 AM  -  10:15 AM

Session 1: Key Note Speech

Chair: Kunlin Jin and Xunming Ji


9:15-9:45   Zaven S. Khachaturian

Novel conceptual model for complex chronic brain disorders of aging

9:45-10:15  Judith Campisi

Cellular senescence, aging and age-related disease

10:15 AM  -10:30 AM

Coffee Break

10:30 AM  -11:30 AM

Key Note Speech


10:30-11:00   David A Greenberg

Vasodegeneration and Neurodegeneration

11:00-11:30  Jianping Jia

Dementia in China

12:00 PM  -1:00 PM

Lunch and Post mounting

1:00 PM  - 3:05 PM

Session 2: Stem Cells, Aging and Disease 

Chair: Ashok K. Shetty and Zhiguo Chen


1:00-1:25 Chun-Li Zhang

Inducing Neurogenesis in the Adult Central Nervous System after Injury

1:25-1:50 Zhongchao Han

Stem cells as anti-degenerative diseases and anti-aging products

tive diseases and anti-aging pr

1:50-2:15 Ashok K. Shetty

Resveratrol therapy in old age prevents memory dysfunction via pro-cognitive and antiinflammatory effects


2:15-2:40 Joanne Conover

A Brain Stem Cell Niche in Aging and Disease

2:40-3:05 Zhiguo Chen

Cell therapy for Parkinson’s Disease – new hope from reprogramming technologies

3:05 PM  - 3:25 PM

Coffee Break

3:25 PM  - 5:30 PM

Session 3: System aging and Disease

Chair: Ilia Stambler and Peichang Wang



3:25-3:50 Ilia Stambler

The use of information theory for the study of aging, aging related diseases and healthy longevity

3:50-4:15 Hiroshi Saito

Acute Inflammatory Diseases in Old Age

4:15-4:40 Peichang Wang

The study of the change & function of DNA polymerase δ in ageing

4:40-5:05 Kyung Jin Min

Lifespan extension by Korean red ginseng and ginseng berry extract


5:05-5:30 Yanning Cai

Circadian rhythm, molecular clock and Parkinson's disease

5:30 pm -6:30 pm  Post session


6:30 PM-8:30 PM   Welcome Dinner (All are welcomed)


Sunday, 2 Nov, 2014  Conference Room No.305

8:30 AM  -  10:30 AM

Session 4: Age-Related Neurodegenerative Diseases

Chair: Michael J Zigmond and Jialin Zheng



8:30-8:50  Veronica Galvan

TOR in Brain Aging and Age-Associated Neurological Disease


8:50-9:10  Hong-Seob So

NAD+ Metabolism in Age-Related Hearing Loss


9:10-9:30 Yukihiro Ohno

New insight into the therapeutic role of serotonergic system in Parkinson’s disease

9:30-9:50  Michael J Zigmond

Influence of physical exercise on age-related neurodegeneration: studies with models of dopamine deficiency

9:50-10:10  Xia Zhang

Interstitial endocannabinoid stream, ischemic tolerance and neuronal death

10:10-10:30 Jialin Zheng

Neural Progenitors by Direct Reprogramming: Strategies for the Treatment of Alzheimer's Diseases

10:30AM  -10:45 AM

Coffee Break

10:45 AM- 12:00 PM

Session 5: Aging and Cardiovascular Diseases

Chair: Raju, Raghavan and Xiaoning Wang


10:45-11:10 Raju, Raghavan *

Understanding aging and injury using a focused microarray


11:10-11:35 Xiaoning Wang

mHealth technology: a efficient way to manage chronic diseases

11:35-12:00 Clive Pai 

Neuroplasticity and Motor Memory Retention for Reduction of Idiopathic Falls among Community-Dwelling Older Adults


12:00 PM  -1:00 PM


1:00 PM  -  3:00 PM

Session 6: Aging and Stroke

Chair: GuoYuan Yang and Heng Zhao


1:00-1:25 Yuchuan Ding

Attenuating Brain Metabolic Dysfunction Improves Stroke Outcome: Is Ethanol A Solution?


1:25-1:50 Xunming Ji

To be named

1:50-2:15 GuoYuan Yang

Therapeutic Mechanism of Endothelial Progenitor Cell Transplantation for Ischemic Stroke


2:15-2:40 Heng Zhao

Significance and Mechanisms of Ischemic Postconditioning against Stroke

2:40-3:00 Changhong  Xing

Effects of lipocalin-2 in the regulation of glial activation and angiogenesis

3:00 PM  -3:15 PM

Coffee Break

3:15 PM  -  5:00 PM

Session 7: Aging, Metabolism, hormone and Diseases

Chair: James W. Simpkins and Holly Brown Borg


3:15-3:35 James W. Simpkins

Estrogens are Potent Neuroprotectants


3:35-3:55 Holly Brown Borg

Growth hormone, methionine metabolism and aging


3:55-4:15 Rui-Hong Wang

Sirt1 Sits at the Crossroad of Cancer, Metabolism and Aging


4:15-4:40 Michael Forster

Caloric Restriction, Brain Aging, and Neurodegenerative Disease



 4:40-5:00 Shaohua Yang

Energy Metabolism as a Target for Neuroprotection and Glioblastoma


5:00 PM  -5:20 PM

Close Mark



Sunday, 2 Nov, 2014  Conference Room No.201

8:30 AM  -  10:35 AM

Session 8: Genetics, Aging and Disease

Chair: Sasanka  Chakrabarti and Yuehua Wei


8:30-8:55   Y-h. Taguchi

Aberrant expression of microRNA according to aging is participating in hepatocarcinogenesis

8:55-9:20    Yuehua Wei

Maf1 regulation of mitochondrial function mediates TOR signaling for longevity


9:20-9:45    Peter Fedichev

The physics behind the Gompertz law, aging, and negligible senescence


9:45-10:10   Sasanka  Chakrabarti

Iron dysregulation and oxidative stress interact to cause increased amyloid beta production in aged rat brain: implications in the pathogenesis of sporadic Alzheimer's disease

10:10-10:35 Nadiya Kazachkova

Variation in the autophagic beclin-1 (BECN1) has a potential to modify onset of

Machado–Joseph disease (MJD/SCA3): a study of the BECN1 gene promoter and the evolutionarily conserved domain (ECD)

10:35 AM  -10:45 AM

Coffee Break

10:45 AM  -  12:00 PM

Session 9: Aging, DNA Damage, Telomeres, Protein oxidation and Disease

ChairRongqiao He and Krishna Sharma


10:45-11:10 Rongqiao He

Endogenous formaldehyde and age-related cognitive impairment

11:10-11:35 Krishna Sharma

Small Heat-Shock Proteins in Lens Aging and Cataract

11:35-12:00 Yulin Deng

To be named

12:00 PM  -1:00 PM



1:00 PM  -  3:05PM

Session 10: Aging, immune and translation

Chair: Abbe N. de Vallejo and Linda J. Van Eldik

1:00-1:25  Abbe N. de Vallejo

Unraveling the Physiologic Construct of Successful Aging; Integral Connectivity Between Immune, Physical, and Cognitive Domains of Function

1:25-1:50  Linda J. Van Eldik

Targeting Inflammatory Cytokine Dysregulation in Neurodegenerative Disorders


1:50-2:15 Yu Zhang 

To be named

2:15-2:40 Dong-Ming Su

Self-reactive T cells participate in inflamm-aging due to compromised thymic negative selection, but not defects in regulatory T cell generation

2:40-3:05 Yong Zhao

Phosphatase Wip1 is essential for the maturation and homeostasis of medullary thymic epithelial cells in mice



3: 05 PM  -3:20 PM

Coffee Break

3:20 PM  -  5:00 PM

Session 11: HIV/AIDS and aging 

Chair: Anuja Ghorpade and Hongjun Li


3:20-3:45Johnny He

HIV-1 Infection and Neurogenesis: Roles of Tat protein

3:45-4:10 Anuja Ghorpade

Astrocyte elevated gene 1 (AEG-1) in HAND and Aging

4:10-4:35 Scott Letendre

Impact of HIV and Aging on the Central Nervous System

4:35-5:00 Hongjun Li

The Study of HIV-1 Associated Dementia by multimode fMRI


5:00 PM  -5:20 PM

Close Mark

Monday3 Nov, 2014 

7:30 am-5:00 pm   The Great Wall trip (invited speakers only)

7:30 am    Please wait in the Lobby

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