Aging & Disease (A&D) is a peer reviewed, open access online journal that aspires to publish novel and high-impact findings on central issues pertaining to the biology of aging, pathophysiology of age-related diseases, and innovative therapies for diseases afflicting the elderly population. The diseases of interest include (but not limited to) Stroke, Alzheimer's disease, Parkinson’s disease, Epilepsy, Dementia, Depression, Cardiovascular Disease, Cancer, Arthritis, Cataract, Osteoporosis, Diabetes and Hypertension. Studies on animal models as well as human tissues or cells are welcome.
Manuscripts in the following areas are of particular interest:
(A) Biology of Aging:
Mechanisms underlying changes in gene & protein expression
Genes, mutations, signaling pathways affecting longevity and successful aging
Mechanisms underlying stem cell proliferation, differentiation and senescence
Role of stress at organismal and cellular levels
Comparative mechanistic studies across species
Efficacy of cognitive and physical exercises on longevity and aging
Effects of dietary-supplements on longevity and aging
(B) Pathophysiology of Age-related Diseases:
Disease pathology using cellular and molecular approaches
Extrinsic and intrinsic factors influencing disease onset, pathology & progression
Effects of physical exercise and environmental enrichment on disease progression
(C) Novel treatments for Diseases afflicting the elderly
Cellular therapies using specific stem, progenitor or precursor cells
Gene therapies using cell grafts or specific vectors
Effects of drugs, vitamins, hormones and antioxidants for treatment of diseases